Tablets + Oral Spray • Published RCT • 67-Day Guarantee
GenF20 Plus – Formula, Clinical Study & Current Price
GenF20 Plus is a two-part healthy-aging supplement system combining tablets with an Alpha GPC oral spray. Its tablet formula includes amino acids, botanicals and related nutrients, while the separate spray provides Alpha GPC; a 12-week finished-product trial measured IGF-1 but did not show a statistically significant overall between-group result.
- Two-part tablets + oral spray system
- Published 12-week randomized placebo-controlled study
- Overall IGF-1 comparison was not statistically significant
- Current verified six-month tier about $58.33 per box
GenF20 Plus at a glance
What GenF20 Plus is built to support
GenF20 Plus is a two-part healthy-aging supplement system combining tablets with an Alpha GPC oral spray. Its tablet formula includes amino acids, botanicals and related nutrients, while the separate spray provides Alpha GPC; a 12-week finished-product trial measured IGF-1 but did not show a statistically significant overall between-group result.
How the formula is intended to work
GenF20 Plus is sold as a two-part system: enteric-coated tablets plus an Alpha GPC oral spray. Existing source material enumerates 16 tablet ingredients, but the amount basis for every listed tablet ingredient is not consistently established across the accessible source set, so missing dose assumptions are not filled in.
GenF20 Plus ingredients & declared dosages
| Ingredient | Declared amount | Manufacturer / label context | Evidence / potential role |
|---|---|---|---|
| GABA | Not verified | Tablet system; exact current amount basis requires live-label confirmation | Included in the multi-ingredient trial formula; the finished-product study measured IGF-1 rather than proving each ingredient contribution. [genf-study] |
| Deer Velvet Antler | Not verified | Tablet system | Animal-derived ingredient included in the formula; no independent finished-product contribution can be isolated. [genf-ingredients] |
| GTF Chromium | Not verified | Tablet system | Included in the current formula listing; current amount basis not inferred where source wording is ambiguous. [genf-ingredients] |
| L-Ornithine HCl | Not verified | Tablet system | Amino acid included in the formula; not evidence by itself for anti-aging or HGH outcomes. [genf-ingredients] |
| L-Arginine HCl | Not verified | Tablet system | Amino acid included in the formula; ingredient rationale does not prove the finished system. [genf-ingredients] |
| L-Glutamine | Not verified | Tablet system | Included in the formula; broad healthy-aging claims are not established from this ingredient alone. [genf-ingredients] |
| L-Glycine | Not verified | Tablet system | Included in the multi-ingredient formula. [genf-ingredients] |
| L-Tyrosine | Not verified | Tablet system | Included in the multi-ingredient formula. [genf-ingredients] |
| L-Lysine HCl | Not verified | Tablet system | Included in the multi-ingredient formula. [genf-ingredients] |
| L-Isoleucine | Not verified | Tablet system | Included in the multi-ingredient formula. [genf-ingredients] |
| L-Valine | Not verified | Tablet system | Included in the multi-ingredient formula. [genf-ingredients] |
| Tribulus terrestris | Not verified | Tablet system | Botanical commonly marketed for male vitality; this does not establish HGH or anti-aging efficacy. [genf-ingredients] |
| Astragalus Root | Not verified | Tablet system | Botanical included in the formula; contribution to the trial result cannot be isolated. [genf-ingredients] |
| Bovine Colostrum | Not verified | Tablet system | Animal-derived ingredient; allergy and dietary suitability may matter. [genf-ingredients] |
| Pituitary (Anterior) Powder | Not verified | Tablet system | Animal-derived glandular ingredient; suitability requires individual consideration. [genf-ingredients] |
| Phosphatidyl Choline | Not verified | Tablet system | Included in the tablet formula. [genf-ingredients] |
| Alpha GPC | Not verified | Separate oral spray component | Current system includes an oral spray; exact current composition should follow the live product label. [genf-ingredients] |
GenF20 Plus price & package options
Package pricing is shown only when it has a dated commercial source. Seller pricing can change without notice.
1 Month
1 box
30-day system
$69.95 / box
Total $69.95
Verify current shipping eligibility at checkout
View 1-Month OfferVerified 2026-09-29 · GenF20web pricing page / current partner checkout
3 Months
3 boxes
90-day system
$66.65 / boxes
Total $199.95
$9.90 versus three single boxes at verified single-box price
Qualifying lower-48 U.S. free shipping shown; verify checkout
View 3-Month OfferVerified 2026-09-29 · GenF20web pricing page / current partner checkout
6 Months
6 boxes
180-day system
$58.33 / boxes
Total $349.95
$69.75 versus six single boxes at verified single-box price
Qualifying lower-48 U.S. free shipping shown; verify checkout
View 6-Month OfferVerified 2026-09-29 · GenF20web pricing page / current partner checkout
Where to buy GenF20 Plus
GenF20 Plus is sold through Leading Edge Health partner channels. Oriqeva is an independent research publication and does not represent the manufacturer. Confirm current checkout totals, shipping and guarantee terms before paying.
Package pricing last verified September 29, 2026; confirm live checkout before purchase.
Safety, interactions & who should be cautious
- The published study reported adverse events including gastrointestinal complaints, headache and skin eruptions; causality was not established for every event. [genf-study]
- The formula contains multiple amino acids, botanicals and animal-derived materials, so medication, allergy and dietary suitability should be reviewed individually. [genf-ingredients][fda-supplements]
- Changes in IGF-1 should not be equated with proven anti-aging, muscle-building or disease-treatment effects. [genf-study]
What the evidence says
| Claim / question | Evidence assessment | Strength |
|---|---|---|
| Has the finished GenF20 Plus system been tested in a randomized controlled trial? | Yes. A 12-week randomized double-blind placebo-controlled study enrolled 70 adults aged 35–65; 61 completed and were analyzed. The primary outcome was serum IGF-1. [genf-study] | moderate |
| Did the study show a significant overall IGF-1 advantage over placebo? | No. The overall between-group IGF-1 comparison was not statistically significant. A favorable statistically significant result was reported after baseline adjustment in the subgroup aged 40 and older. [genf-study] | limited |
| Did the study prove broad anti-aging or HGH benefits? | No. The study used IGF-1 as a marker and did not establish broad clinical benefits for memory, libido, energy, sleep, body composition or disease outcomes over placebo. [genf-study] | limited |
Potential strengths
- A randomized placebo-controlled finished-product study is available.
- Two-part product identity and current package structure are clear.
- Current pricing and 67-day guarantee are documented.
Important limitations
- Overall primary IGF-1 comparison was not statistically significant.
- Favorable age-40-plus finding came from an adjusted subgroup analysis.
- Current amount basis for every listed tablet ingredient is not consistently established in accessible source material.
How strong is the GenF20 Plus evidence?
GenF20 Plus has more direct evidence than many healthy-aging supplements because the complete system was evaluated in a randomized placebo-controlled study. The key nuance is essential: the overall IGF-1 difference between groups was not statistically significant, while the favorable finding came from an adjusted analysis of participants aged 40 and older. That makes the study hypothesis-supporting rather than definitive. Oriqeva also avoids translating IGF-1 changes into guaranteed HGH elevation or broad anti-aging outcomes and keeps unresolved contemporary dose-basis details explicit instead of guessing.
Frequently asked questions about GenF20 Plus
What is GenF20 Plus?
A two-part dietary supplement system combining tablets with an Alpha GPC oral spray, marketed for healthy-aging and HGH-support positioning.
Is GenF20 Plus clinically studied?
Yes. A randomized double-blind placebo-controlled 12-week study evaluated serum IGF-1 and other outcomes.
Does GenF20 Plus increase HGH?
The study measured IGF-1 as a marker related to growth-hormone activity. The overall between-group IGF-1 result was not statistically significant, so it should not be presented as proof of broad HGH increases.
How much does GenF20 Plus cost?
The latest verified project pricing is $69.95 for one month, $199.95 for three months and $349.95 for six months. Verify the live checkout because offers can change.
What is the GenF20 Plus guarantee?
Current seller terms describe a 67-day guarantee with return conditions and shipping exclusions.
Where can I buy GenF20 Plus?
Oriqeva links to the current Leading Edge Health partner checkout and is not the manufacturer or seller.
References
- Effect of GenF20 Plus on serum IGF-1 levels in healthy adults: a randomized, double-blind, placebo-controlled clinical trial — Open Access Journal of Clinical Trials / Dove Medical Press (2015). Source
- GenF20 Plus Ingredients — GenF20 Plus / Leading Edge Health. Source
- GenF20 Plus Price & Package Comparison — GenF20web. Source
- GenF20 Plus — Leading Edge Health. Source
- Information for Consumers on Using Dietary Supplements — U.S. Food and Drug Administration. Source
- Information for Consumers on Using Dietary Supplements — FDA. Source
Change history
- — Added evidence-reviewed GenF20 Plus record with trial interpretation, anti-aging category mapping, current packages and affiliate tracking sub-ID O.
- — Expanded manufacturer-declared ingredient rows and authoritative evidence references; refreshed page freshness metadata after the material content update.